AAU Update

PhD defense, Kresten Wendell Rickers

The Department of Clinical Medicine, Aalborg University and Aalborg University Hospital are pleased to invite to PhD defense by MD, Kresten Wendell Rickers, who will defend the thesis entitled: New Interventions for Lumbar Disc Herniation

Tidspunkt

18.06.2021 kl. 13.00 - 16.00

Beskrivelse

The PhD defense will take place

Friday 18 June 2021 at 13:00

In the auditorium, Medicinerhuset, Aalborg University Hospital
Participants should have a coronapas to join the defense.

And virtually via teams (registration by email to: inst.klinisk.phd@dcm.aau.dk)

 

Supervisors

Associate Prof. Søren Eiskjær MD
Department of Clinical Medicine, Aalborg University
Aalborg University Hospital, Denmark

Associate Prof. Peter Heide Pedersen MD, PhD
Department of Clinical Medicine, Aalborg University
Aalborg University Hospital, Denmark

Michael Bendtsen MD, PhD,
Aarhus University Hospital, Denmark


Assessment Committee

Associate Prof. Thomas Jakobsen MD, PhD, DMsc
Department of Clinical Medicine, Aalborg University
Aalborg University Hospital, Denmark (Chairman)

Associate Prof. Peter Helmig MD, PhD
Department of Clinical Medicine, Aarhus University
Aarhus University Hospital, Denmark

Prof. Ilkka Helenius, MD, PhD, DMsc
Department of Orthopaedics and Traumatology
University of Helsinki and Helsinki University Hospital
Helsinki, Finland

 

About the PhD thesis

Lumbar disc herniation is one of the most common back disorders. It most often affects people aged 20-40 years and can lead to long-term sick leave. Surgery to remove the prolapse is an effective treatment for lack of symptom improvement after 6-12 weeks. It provides relief from pain and provides a faster return to work. Despite good results, there is a relatively high proportion who needs resurgery, most often due to reherniation.

The PhD dissertation is based on three studies: 1) a biomechanical test of an experimental method for repairing the outer ring of the disc, 2) a clinical trial that examined a novel implant for use in conjunction with discectomy, 3) a systematic review of the literature as well as network meta-analysis, to compare all current surgical methods and conservative treatment.

The project found that the experimental method had a beneficial biomechanical profile, unfortunately the repair was not effective enough to prevent reherniation. In the clinical trial, the implant tested proved to be equally safe as standard discectomy. Due to the size of the trial, it was not possible to measure a difference in efficiency. In the systematic review of the literature, 32 studies were identified, which compared 8 treatments. The quality of the studies was variable. The network meta-analysis showed that conservative treatment as well as percutaneous discectomy performed worse than the usual surgical treatments.

The dissertation concludes that surgery for disc herniation is still indicated if there is the lack of effect of conservative treatment. The experimental and new methods studied gave promising results, but it was not possible to show that they were better than the current treatment.

Arrangør

Department of Clinical Medicine, Aalborg University

Adresse

Medicinerhuset, Mølleparkvej 4, 9000 Aalborg, Auditoriet

Tilmeld dig til

inst.klinisk.phd@dcm.aau.dk

Kontakt AAU

Har du spørgsmål vedr. arrangementskalenderen på AAU, kan du kontakte AAU Kommunikation

E-mail: aaukommunikation@adm.aau.dk